A mathematical model of tissue replacement during epidermal wound healing
نویسندگان
چکیده
منابع مشابه
A mathematical model of intercellular signaling during epithelial wound healing.
Recent experiments monitoring the healing process of wounded epithelial monolayers have demonstrated the necessity of MAPK activation for coordinated cell movement after damage. This MAPK activity is characterized by two wave-like phenomena. One MAPK "wave" that originates immediately after injury, propagates deep into the cell sheet, away from the edge, and then rebounds back to the wound inte...
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Epidermal repair during wound healing is under investigation at both the light and electron microscopic levels. Suction-induced subepidermal blisters have been employed to produce two complementary model wound healing systems. These two model systems are: (a) intact subepidermal blisters, and (b) opened subepidermal blisters (the blister roof was removed immediately after induction, leaving an ...
متن کاملSpatial dynamics for a model of epidermal wound healing.
In this paper, we consider the spatial dynamics for a non-cooperative diffusion system arising from epidermal wound healing. We shall establish the spreading speed and existence of traveling waves and characterize the spreading speed as the slowest speed of a family of non-constant traveling wave solutions. We also construct some new types of entire solutions which are different from the travel...
متن کاملModels of epidermal wound healing.
The spreading of cells across the surface of an epidermal wound enables epidermal migration to be studied independently of the wound contraction that occurs in deeper wounds. In particular, the stimulus for the increase in epidermal mitosis during would healing is uncertain. Our modelling suggests that biochemical regulation of mitosis is fundamental to the process, and that a single chemical w...
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ژورنال
عنوان ژورنال: Applied Mathematical Modelling
سال: 2003
ISSN: 0307-904X
DOI: 10.1016/s0307-904x(02)00100-2